Bringing together biologists, physicists, mathematicians, designers and others to elucidate the role of curvature in biological systems
Cells and tissues not only interact and respond to the shape of their physical environment but they can also change it. Shape can be modified by processes such as growth, remodeling and/or the development of active forces by a living tissue. A key descriptor of shape is the curvature of the surface, and recent research has indeed shown that curvature not only is controlled by cells and tissues, but also plays an important role as a physical signal that can guide cell and tissue response. The difficulty of this topic is that it requires knowledge coming from a wide range of natural science disciplines, such as biology, mathematics, physics and materials science.
Three successful workshops (2019,2020 and 2021) show that there is a vibrant community of people interested in learning and solving problems related to the interplay between curvature and biology. Our goal is to keep these people together communicating and to make a useful platform to help people stay and get in contact with each other, but also to provide useful resources for teaching and research.
Check out this review paper:
"Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales"
Thanks a lot to all co-authors for this group effort!
Alfredo Sciortino won the Best Image Award during CurvoBio2022 Workshop
Active patterns formed by actin filaments gliding on the inner surface of spherical lipid vesicles